Immunoglobulin structure

Last year I said that a full paper detailing all the haemoglobin work would be the next project for this blog. As it happens I realised a few months ago that IgG (an immunoglobulin) is like haemoglobin in being an α₂β₂ tetramer and so I explored tetrahedral rearrangements of the published crystal structure. This project has been very successful. I will present the IgG results on this blog before I complete the larger haemoglobin document.

Rotation-translation operators.

I have changed the form of the rotation and translation operations used to present the results of my earlier studies on neuraminidases, galactose oxidase and haemoglobin. The Convention used by the International Union of Crystallographers is that the rotation should precede the translation. I have now amended the papers linked to this blog to conform with that Convention. Previously I specified the translation before the rotation. The one paper I have not yet amended is the older pdf version of the neuraminidase paper.

I just noticed tonight that some of the punctuation and special characters in my linked htm files were not shown by Internet Explorer. Sorry about that. I have fixed the problems and added a few links back to this page to aid navigation. I'm still thinking about a novel approach to writing up the haemoglobin work. I think I have a good idea. I've also noticed that the original Biophysical Journal paper (see the bottom of this blog) is getting more citations as the years pass.