Symmetry, Pseudo-symmetry and Evolution in Protein Structures

This poster was displayed at BioPhysChem 2011 at the University of Wollongong 3-6 December 2011. Reasoning from the effect of Natural Selection on symmetry, it shows examples of the arrangement of subunits in a complex and the alignment of "barrel" structures pointing towards the centre of the complex. Click on the title of this post or here to view the poster.

Effect of Crystallization on Protein Quaternary Structure

This talk was given at BioPhysChem2011 (3-6 December at the University of Wollongong) on 6 December 2011. It deals quantitatively with the expected changes to protein structure when the protein-in-water phase is changed to a water-in-protein phase during crystallization. For the first time there is a chemical explanation of why crystal structures differ from native structures as detailed throughout this blog. Click on the title of this post or here to view the slides, including animation.